Im am running Windows Vista with Office 2007 for about 1 year with no 
problems.  
This weekend i was trying to open an excel file (.xls) attached to my email 
account (gmail) and I got an error message "cannot find file 
path....C:/users/steve/....../temporary internet files/...."
If i save the file directly to my computer, i am still not able to open the 
file.  I can however open files that I had before.
I can open word, pdf and powerpoint attachments.